Ketamine for couples therapy is making waves in both clinical care and pop culture—with real-life success stories like Jen and Zac Affleck’s journey on Secret Lives of Mormon Wives. On the hit reality show Secret Lives of Mormon Wives, Jen and Zac Affleck shared how ketamine-assisted therapy at Kadelyx was a turning point in their healing journey, both individually and as a couple.
Jen and Zac Affleck Use Ketamine at Kadelyx
The Secret Lives of Mormon Wives is a reality television series created for Hulu. The show follows a group of eight TikTok influencers, known as “MomTok,” as they deal with issues like faith, identity, marriage, and mental health.
On Season Two of the show, Jen Affleck and her husband Zac discuss their journey with ketamine therapy. The show also shows a short clip of the two undergoing an intramuscular (IM) ketamine infusion at our state-of-the-art clinic in Phoenix, Arizona.
Jen came to Kadelyx hoping for a breakthrough in her personal healing and to help improve her marriage. She had extensively explored therapy, but was still struggling with trauma. Zac came across ketamine therapy when studying medicine, and the couple decided Kadelyx would be the best place, given the location and “zen” settings.
The couple underwent seven sessions of ketamine infusions, each paired with integration work, intention-setting, and professional support from our multidisciplinary care team.
Zac called it “the hardest form of therapy” because of its emotional depth. He said, “It makes you face your true feelings, your true emotions, your insecurities, your weaknesses.”
But that courage paid off. As Zac explained:
“When I think of Kadelyx, that was a pivotal moment in our healing… It kept our marriage together, it kept our family together, and helped me learn a lot about myself.”
Demi Engemann on Ketamine for Relationship Growth
Demi Engemann also shared her experience on Season 1 of Secret Lives. In a conversation with co-star Whitney Leavitt, she described her ketamine session as therapy for “physical trauma or emotional trauma,” noting how the experience helped her tap into “truths about yourself you wouldn’t otherwise admit.”
Later, on The Viall Files podcast, Demi revealed that she and her husband, Brett, had also used ketamine therapy together. She said, “Everyone I talked to they’re like, ‘We’re kind of struggling [and] things are getting a little bit dull.’ Go do ketamine with your spouse.”
The Science Behind Ketamine for Couples Therapy
Though ketamine is most widely known for treating mental health disorders, it’s increasingly being explored for couples and relationship-based therapy.
Ketamine increases neuroplasticity, the brain’s ability to reorganize itself. Neuroplastic mechanisms can help disrupt unhealthy thought patterns and behaviors that may be causing problems in a relationship. Studies show that ketamine reduces negative affective bias, which is a tendency to think about things negatively.
Ketamine also has psychoactive effects. When paired with skilled therapeutic support, these effects can help people process trauma, which may be contributing to relationship problems. People can also become more connected to their emotions and have a greater sense of empathy following ketamine.
Ketamine for Couples Therapy at Kadelyx
At Kadelyx, we offer ketamine-assisted therapy designed specifically for couples seeking a deeper connection and emotional healing. Each session lasts approximately three hours and is administered via an IM injection. This administration is less invasive than traditional intravenous (IV) infusions and has a more gentle onset.
Our couples program begins with intentional preparation to ensure each session is tailored to your unique relational goals. Equally important is our integration process, where insights gained during the session are explored and applied through guided therapeutic support, helping you sustain and deepen the benefits of your experience together.
If you want to explore how ketamine could benefit your relationship, get in touch with our team at Kadelx today.
