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Ketamine Research Studies

Ketamine for Depression

Ketamine outperforms ECT for Treatment Resistant Depression

https://www.nejm.org/doi/full/10.1056/NEJMoa2302399.

 

Examining ketamine as a paradigm shift in Depression

https://doi.org/10.1016/j.neuron.2019.02.005

 

Ketamine normalizes brain function on fMRI for patients with depression

https://pubmed.ncbi.nlm.nih.gov/30826253/

 

Six ketamine treatment regimen for depression outperformed single ketamine treatment

https://doi.org/10.1177/0269881119827811

 

Multiple ketamine treatments for depression are more durable than single treatment

https://www.nature.com/articles/s41398-020-00897-0

Ketamine for Anxiety

Systematic review shows higher dose ketamine results in improved functioning in Anxiety Spectrum Disorders 

https://doi.org/10.1177/20451253211056743

 

Meta-analysis shows rapid and sustained improvements in anxiety using ketamine

https://doi.org/10.1177/02698811231161

 

Higher dose ketamine treats refractory anxiety disorders

https://doi.org/10.1177/0269881117705089

Ketamine for PTSD

Ketamine may help rewrite traumatic memories in PTSD

https://www.nature.com/articles/s41386-023-01606-3

 

Significant improvements in ketmine for PTSD and comorbid depression

https://www.psychiatrist.com/jcp/repeated-ketamine-infusions-for-comorbid-ptsd-and-trd/

 

Review of ketamine as a treatment for PTSD

https://www.drugsincontext.com/ketamine-as-treatment-for-post-traumatic-stress-disorder:-a-review/

Ketamine for Eating Disorders

Evidence for ketamine as an agent for the treatment of eating disorders

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963252/

 

Narrative exploration of ketamine as a treatment for Anorexia Nervosa

https://www.mdpi.com/2072-6643/13/11/4158

Ketamine for Pain

Improvements in pain seen alongside depression increase overall functioning

https://doi.org/10.1016/j.jad.2023.04.122

 

Pain improvements and opioid sparing properties of ketamine

https://www.ncbi.nlm.nih.gov/books/NBK539824/

Ketamine for Personal Growth

Ketamine has mood-independent pro-cognitive effect on processing speed

https://pubmed.ncbi.nlm.nih.gov/34715598/

 

Review of neuroplasticity, increased functional connectivity, and anti-inflammatory effects with ketamine

https://doi.org/10.1016/j.jad.2022.12.021

 

Ketamine exhibits anti-inflammatory effects

https://doi.org/10.1177/02698811211026426

Ketamine for End of Life Care

Systematic review recommends starting patients on injectable ketamine and transitioning to oral ketamine

https://pubmed.ncbi.nlm.nih.gov/31090477/

 

Ketamine is an effective agent palliative care in cancer patients with refractory pain

https://www.ncbi.nlm.nih.gov/books/NBK539824/

Racemic Ketamine vs Esketamine (Spravato)

Meta-analysis finds racemic ketamine outperforms esketamine in all measures

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00304-8/fulltext

 

Racemic ketamine outperforms esketamine in Veterans with Depression

https://pubmed.ncbi.nlm.nih.gov/35122282/

Quality of Experience Matters

Experiences of Awe increased antidepressant effects of ketamine

https://doi.org/10.1016/j.bpsgos.2024.100316

 

Depth of dissociation matters

https://doi.org/10.1016/j.jad.2014.02.017

Discover the ketamine therapy option that best suits your needs. Contact Kadelyx Health today to schedule a consultation.